Parthenolide induces apoptosis via TNFRSF10B and PMAIP1 pathways in human lung cancer cells
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منابع مشابه
Parthenolide induces apoptosis via TNFRSF10B and PMAIP1 pathways in human lung cancer cells
BACKGROUND Parthenolide (PTL) is a sesquiterpene lactone which can induce apoptosis in cancer cells and eradicate cancer stem cells such as leukemia stem cells, prostate tumor-initiating cells and so on. However, the mechanism remains largely unclear. METHODS Lung cancer cells were treated with parthenolide and the cell lysates were prepared to detect the given proteins by Western Blot analys...
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Econazole nitrate (EN), a synthetic compound, is now in use as a routine antifungal drug. EN was shown to have antitumor effect, the tumor cell killing mechanisms, however, remain unclear. In this research, the apoptosis-inducing effect of EN on MCF-7 cells was investigated. The results showed that EN inhibited the proliferation of MCF-7 cells in a time- and dose-dependent manner by MTT method ...
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ژورنال
عنوان ژورنال: Journal of Experimental & Clinical Cancer Research
سال: 2014
ISSN: 1756-9966
DOI: 10.1186/1756-9966-33-3